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A giant Müllerian duct cyst in the perineum: a case report

Xianghu Meng, Jihong Liu, Xiao Yu, Shaogang Wang, Cong Liu, Zhangqun Ye

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 440-443 doi: 10.1007/s11684-012-0222-6

Abstract: Treatments of Müllerian duct cysts depend on their sizes and symptoms.

Keywords： Müllerian duct cyst     clinical symptoms     diagnosis    

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Prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in Northeast Iran

Fatemeh Mehravar,Soheil Rafiee,Behnaz Bazrafshan,Mahmoud Khodadost

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 345-350 doi: 10.1007/s11684-016-0462-y

Abstract: This study aimed to examine the prevalence of asthma symptoms in Golestan schoolchildren aged 6&ndashAsthma symptoms were assessed using the questionnaire of the International Study of Asthma and Allergiesregression model was used to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) of the asthma symptomsThe prevalence rates of “current asthma” symptoms and “asthma ever” in all theThis study shows that the prevalence of the asthma symptoms in boys is lower than that in girls in both

Keywords： asthma     asthma symptoms     epidemiology     childhood     chronic disease    

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Recombinant protein diannexin prevents preeclampsia-like symptoms in a pregnant mouse model via reducing

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 919-931 doi: 10.1007/s11684-021-0918-6

Abstract: Moreover, in vivo results showed that diannexin could prevent PE-like symptoms by decreasing MPs

Keywords： preeclampsia     recombinant protein diannexin     microparticle     NLRP3 inflammasome     phosphatidylserin    

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Clinical Characteristics and Outcomes of Severe or Critical COVID-19 Patients Presenting No RespiratorySymptoms or Fever at Onset Article

Juanjuan Xu, Zhengrong Yin, Yu Liu, Sufei Wang, Limin Duan, Yi An, Jinshuo Fan, Tingting Liao, Yang Jin, Jianguo Chen

Engineering 2021, Volume 7, Issue 10,   Pages 1454-1460 doi: 10.1016/j.eng.2020.09.009

Abstract: This retrospective study presents the clinical, laboratory, and radiological profiles, treatments, andoutcomes of atypical COVID-19 patients without respiratory symptoms or fever at onset.were obtained from the electronic medical records of severe or critical patients without respiratory symptomsOf the severe or critical patients, ten (1.1%) presented without respiratory symptoms or fever at admissionIn summary, some severe or critical COVID-19 patients were found to have no respiratory symptoms or fever

Keywords： SARS-CoV-2     COVID-19     Atypical clinical characteristics    

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Gastric Mucosal Microbiota in Patients with Liver Cirrhosis and Its Associations with Gastrointestinal Symptoms Article

Yanfei Chen, Jing Guo, Chunlei Chen, Ding Shi, Daiqiong Fang, Feng Ji, Lanjuan Li

Engineering 2021, Volume 7, Issue 4,   Pages 507-514 doi: 10.1016/j.eng.2020.04.014

Abstract: Patients in Cluster_2 had more severe gastrointestinal symptoms and a higher rate of previous endoscopicmicrobiota showed considerable heterogeneity, associations between specific gastric microbiota and clinicallead to a distinct structure of the gastric mucosal microbiota, thus aggravating the gastrointestinal symptoms

Keywords： Microbiome     Liver cirrhosis     Symptoms     Varices     Gastric endoscopy    

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Characterization of hidden rules linking symptoms and selection of acupoint using an artificial neural

Won-Mo Jung, In-Soo Park, Ye-Seul Lee, Chang-Eop Kim, Hyangsook Lee, Dae-Hyun Hahm, Hi-Joon Park, Bo-Hyoung Jang, Younbyoung Chae

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 112-120 doi: 10.1007/s11684-017-0582-z

Abstract: The pattern recognition process that pertains to symptoms and diseases and informs acupuncture treatmentin a clinical setting was explored.A total of 232 clinical records were collected using a Charting Language program.classification or pattern recognition and for the prediction and modeling of acupuncture treatment based on clinicalThe relationship between symptoms and selected acupoints could be systematically characterized through

Keywords： acupuncture     indication     neural network     pattern identification     prediction    

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Ontological reconstruction of the clinical terminology of traditional Chinese medicine

Li Ma,Baoyan Liu,Qi Xie,Shusong Mao,Zhiwei Cui

Frontiers of Medicine 2014, Volume 8, Issue 3,   Pages 358-361 doi: 10.1007/s11684-014-0348-9

Abstract:

This study proposes the ontological reconstruction of the current clinical terminology of traditionalof preliminary work related to the said reconstruction, including the ontology-based analysis of TCM clinicalWe conclude that the ontological reconstruction of TCM clinical terminology provides a proper translation

Keywords： ontology     traditional Chinese medicine     clinical terminology    

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The clinical impact of tricuspid regurgitation in patients with a biatrial orthotopic heart transplant

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 527-533 doi: 10.1007/s11684-022-0967-5

Abstract: In this study, we aim to elucidate the clinical impact and long-term course of tricuspid regurgitation

Keywords： orthotopic heart transplant     tricuspid regurgitation     clinical impact     biatrial heart transplantation    

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Obesity-related glomerulopathy: pathogenesis, pathologic, clinical characteristics and treatment

Tianhua Xu, Zitong Sheng, Li Yao

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 340-348 doi: 10.1007/s11684-017-0570-3

Abstract: A slow increase of subnephrotic proteinuria (<3.5 g/d) is the most common clinical manifestation of

Keywords： obesity-related glomerulopathy     pathogenesis     pathologic     clinical characteristics    

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Coronavirus disease 2019 (COVID-19): a clinical update

Min Zhou, Xinxin Zhang, Jieming Qu

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 126-135 doi: 10.1007/s11684-020-0767-8

Abstract: promising antivirals, convalescent plasma transfusion, and tocilizumab needs to be investigated by ongoing clinical

Keywords： coronavirus disease 2019     epidemiology     pathology     radiology     clinical characteristics     treatment    

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Hypertension in patients with CKD in China: clinical characteristics and management

Guangyan Cai, Xiangmei Chen

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 307-309 doi: 10.1007/s11684-017-0578-8

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Bone metastasis of hepatocellular carcinoma: facts and hopes from clinical and translational perspectives

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 551-573 doi: 10.1007/s11684-022-0928-z

Abstract: Patients with hepatocellular carcinoma (HCC) and bone metastasis (BM) suffer from greatly reduced life quality and a dismal prognosis. However, BM in HCC has long been overlooked possibly due to its relatively low prevalence in previous decades. To date, no consensus or guidelines have been reached or formulated for the prevention and management of HCC BM. Our narrative review manifests the increasing incidence of HCC BM to sound the alarm for additional attention. The risk factors, diagnosis, prognosis, and therapeutic approaches of HCC BM are detailed to provide a panoramic view of this disease to clinicians and specialists. We further delineate an informative cancer bone metastatic cascade based on evidence from recent studies and point out the main factors responsible for the tumor-associated disruption of bone homeostasis and the formation of skeletal cancer lesions. We also present the advances in the pathological and molecular mechanisms of HCC BM to shed light on translational opportunities. Dilemmas and challenges in the treatment and investigation of HCC BM are outlined and discussed to encourage further endeavors in the exploration of underlying pathogenic and molecular mechanisms, as well as the development of novel effective therapies for HCC patients with BM.

Keywords： HCC     bone     osteotropism     clinical     basic researches     advances    

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Heterogeneity of the tumor immune microenvironment and clinical interventions

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 617-648 doi: 10.1007/s11684-023-1015-9

Abstract: Heterogeneity of the tumor immune microenvironment and clinical interventions

Keywords： Heterogeneity tumor immune    

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Pathogen evolution, prevention/control strategy and clinical features of COVID-19: experiences from China

Frontiers of Medicine doi: 10.1007/s11684-023-1043-5

Abstract: The overall clinical features of variants of concern (VOC), heterogeneity in the clinical manifestations

Keywords： coronavirus disease 2019     SARS-CoV-2     epidemiology     clinical features    

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Genetic and clinical markers for predicting treatment responsiveness in rheumatoid arthritis

Xin Wu, Xiaobao Sheng, Rong Sheng, Hongjuan Lu, Huji Xu

Frontiers of Medicine 2019, Volume 13, Issue 4,   Pages 411-419 doi: 10.1007/s11684-018-0659-3

Abstract: These predictors include but are certainly not limited to genetic variations, clinical factors, and demographicHowever, no clinical application is currently available.

Keywords： rheumatoid arthritis     gene     clinical markers     therapy    

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Title Author Date Type Operation

A giant Müllerian duct cyst in the perineum: a case report

Xianghu Meng, Jihong Liu, Xiao Yu, Shaogang Wang, Cong Liu, Zhangqun Ye

Journal Article

Prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in Northeast Iran

Fatemeh Mehravar,Soheil Rafiee,Behnaz Bazrafshan,Mahmoud Khodadost

Journal Article

Recombinant protein diannexin prevents preeclampsia-like symptoms in a pregnant mouse model via reducing

Journal Article

Clinical Characteristics and Outcomes of Severe or Critical COVID-19 Patients Presenting No RespiratorySymptoms or Fever at Onset

Juanjuan Xu, Zhengrong Yin, Yu Liu, Sufei Wang, Limin Duan, Yi An, Jinshuo Fan, Tingting Liao, Yang Jin, Jianguo Chen

Journal Article

Gastric Mucosal Microbiota in Patients with Liver Cirrhosis and Its Associations with Gastrointestinal Symptoms

Yanfei Chen, Jing Guo, Chunlei Chen, Ding Shi, Daiqiong Fang, Feng Ji, Lanjuan Li

Journal Article

Characterization of hidden rules linking symptoms and selection of acupoint using an artificial neural

Won-Mo Jung, In-Soo Park, Ye-Seul Lee, Chang-Eop Kim, Hyangsook Lee, Dae-Hyun Hahm, Hi-Joon Park, Bo-Hyoung Jang, Younbyoung Chae

Journal Article

Ontological reconstruction of the clinical terminology of traditional Chinese medicine

Li Ma,Baoyan Liu,Qi Xie,Shusong Mao,Zhiwei Cui

Journal Article

The clinical impact of tricuspid regurgitation in patients with a biatrial orthotopic heart transplant

Journal Article

Obesity-related glomerulopathy: pathogenesis, pathologic, clinical characteristics and treatment

Tianhua Xu, Zitong Sheng, Li Yao

Journal Article

Coronavirus disease 2019 (COVID-19): a clinical update

Min Zhou, Xinxin Zhang, Jieming Qu

Journal Article

Hypertension in patients with CKD in China: clinical characteristics and management

Guangyan Cai, Xiangmei Chen

Journal Article

Bone metastasis of hepatocellular carcinoma: facts and hopes from clinical and translational perspectives

Journal Article

Heterogeneity of the tumor immune microenvironment and clinical interventions

Journal Article

Pathogen evolution, prevention/control strategy and clinical features of COVID-19: experiences from China

Journal Article

Genetic and clinical markers for predicting treatment responsiveness in rheumatoid arthritis

Xin Wu, Xiaobao Sheng, Rong Sheng, Hongjuan Lu, Huji Xu

Journal Article